Streptococcus pneumoniae
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Classification
Higher order taxa
Domain: Bacteria
Phylum: Firmicutes
Class: Diplococci
Order: Lactobacillales
Family: Streptococcaceae
Genus: Streptococcus
Species
Species: S. pneumoniae
Description and significance
Streptococcus pneumoniae, also called pneumococcus, is a gram-positive, pathogenic bacterium capable of causing numerous infections. It the most common cause of pneumonia and bacterial meningitis, and is commonly found in the upper respiratory tract of humans. S. pneumoniae is shaped like a lancet, a type of knife with a short wide two-edged blade. It is alpha hemolytic (a classification method using the breakdown of red blood cells) and is usually between 0.5 and 1.25 micrometers in size.
S. pneumoniae was first isolated in 1881 simultaneously by U.S. Army physician George Sternberg and French chemist Louis Pasteur. In 1928 by Frederick Griffith and 1944 by Avery, MacLeod and McCarty, S. pneumoniae was used to prove that genetic material consists of DNA.
Genome structure
S. pneumoniae has a 2,160,837 base pair genome sequence. Its chromosome is circular and has 2236 coding regions. Approximately 5% of the genome is composed of insertion sequences that may contribute to genome rearrangements through uptake of foreign DNA. S. pneumoniae has shown a significant increase in antibiotic resistance over the past few decades, due to its rapid growth rate and genetic rearrangements.
Cell structure and metabolism
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Ecology
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Pathology
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Application to Biotechnology
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Current Research
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References