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In medicine, sepsis is a form of "systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by hypotension despite adequate fluid infusion, it is called septic shock."[1]


Polymerase chain reaction may add to blood cultures in identifying pathogens.[2]


Prognosis can be measured with the PIRO staging model.[3]


  1. Anonymous (2015), Sepsis (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. Bloos F, Hinder F, Becker K, Sachse S, Dessap AM, Straube E et al. (2010). "A multicenter trial to compare blood culture with polymerase chain reaction in severe human sepsis.". Intensive Care Med 36 (2): 241-7. DOI:10.1007/s00134-009-1705-z. PMID 19924398. Research Blogging.
  3. Rubulotta F, Marshall JC, Ramsay G, Nelson D, Levy M, Williams M (April 2009). "Predisposition, insult/infection, response, and organ dysfunction: A new model for staging severe sepsis". Crit. Care Med. 37 (4): 1329–35. DOI:10.1097/CCM.0b013e31819d5db1. PMID 19242329. Research Blogging.