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A list of key readings about Schizophrenia.
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Provides an overview of epidemiological, pharmacological, genetic and cognitive aspects of schizophrenia, a synthesis of the state of diagnosis, disease progression and therapy as well as a discussion of the overlap with other psychiatric disorders, such as bipolar disorder, depression, schizoaffective disorder and autism.
Introductory part to a series of four articles on what was known about schizophrenia at the time of writing. Part 2 is on Epidemiology and etiology, part 3 on Neurobiology and part 4 on Clinical features and conceptualizations of this complex topic.
The series is structured around a list (given in part 1) of facts on schizophrenia, which are assessed in terms of reproducibility, relevance to the illness and how long they had been known
Provides an analysis of correlations between 10 volume-based brain morphometric measures and 32 single-nucleotide polymorphisms in 25 schizophrenic patients, tentatively identifying RELN, the gene encoding reelin, as possibly involved in ventricular enlargement, and PCDH12, the gene encoding protocadherin 12, as a candidate for genetic invovlvement in gyrification.
Provides a brief biography of Paul Eugen Bleuler, along with a portrait and the etymology of the word schizophrenia.
Provides a brief synthesis of expert opinions on specific aspects of research into the biological mechanisms underlying schizophrenia, along with a perspective from non-experts.
A meta analysis of incidence rates of schizophrenia across human cultures, which range from below 1 in 1000 people in the Amish to about 2-5 in much of the world, and up to over 15 in some parts of Sweden and Ireland. These numbers rise further still if one only considers the susceptible age range (usually taken as between 16 and 40 years).