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Ritonavir structure.jpg
IUPAC name: see chemistry section
Synonyms: Norvir®,Norvir Sec®
Formula: C37H48N6O5S2

 Uses: HIV

 Properties: protease inhibitor

 Hazards: see drug interactions

Mass (g/mol): CAS #:
720.9442 155213-67-5

Ritonavir, sold under the brand names Norvir® and Norvir Sec®, and as a mixture with Lopinavir called Kaletra®, is a protease inhibitor used to treat HIV/AIDS by disrupting the reproductive cycle of the virus. Ritonavir binds to and inhibits the HIV-1 viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles. Protease inhibitors like ritonavir are almost always used in combination with at least two other anti-HIV drugs.


Its chemical name is 1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan- 2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-di(phenyl)hexan- 2-yl]carbamate and its chemical formula is C37H48N6O5S2.

External Links

The most up-to-date information about Ritonavir and other drugs can be found at the following sites.