Proteinuria

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In medicine, proteinuria is "the presence of proteins in the urine, an indicator of kidney diseases."[1]

Contents

Diagnosis

Spot protein/creatinine ratio

One study found that in the presence of stable renal function, a protein/creatinine ratio:[2]

  • > 3.5 (mg/mg) indicates nephrotic-range proteinuria
  • < 0.2 is within normal limits

Spot urine albumin/creatinine ratio

In adults, albuminuria is a more sensitive than total protein in detecting chronic kidney disease from many glomerular diseases.[3]

  • <30 mg/g is a normal albumin-creatinine ratio
  • 30-300 mg/g is microalbuminuria

References

  1. ↑ Anonymous, (2009) Proteinuria (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. ↑ Ginsberg JM, Chang BS, Matarese RA, Garella S (1983). Use of single voided urine samples to estimate quantitative proteinuria.. N Engl J Med 309 (25): 1543-6. PMID 6656849.
  3. ↑ National Kidney Foundation (2002). K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification.. Am J Kidney Dis 39 (2 Suppl 1): S1-266. PMID 11904577.
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