Linezolid

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Linezolid is the first commercially available antibiotic of the oxazolidinone class, approved for complex vancomycin-resistant Enterococcus faecium infections, methicillin-resistant Staphylococcus aureus, and complex Streptococcus pyogenes and S. agalactiae infections. It is approved for complex skin and soft tissue infections, and for pneumonias.

It has little activity against Gram-negative organisms. The drug can be given intravenously or orally.