Intracranial aneurysm

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In medicine, intracranial aneurysms are "abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in Circle of Willis at the base of the brain. Vessel rupture results in subarachnoid hemorrhage or intracranial hemorrhages. Giant aneurysms (>2.5 cm in diameter) may compress adjacent structures, including the oculomotor nerve. (From Adams et al., Principles of Neurology, 6th ed, p841)[1][2]

Prevalence

Almost 2% of adults may have intracranial aneurysms by magnetic resonance imaging.[3] Most are less than 7 mm in size and located in the anterior circulation.

Prognosis

The likelihood of rupture increases if a history of prior hemorrhage, larger size of the aneurysm, and location in posterior circulation.[4]

References

  1. Anonymous (2015), Intracranial aneurysm (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. Brisman JL, Song JK, Newell DW (August 2006). "Cerebral aneurysms". N. Engl. J. Med. 355 (9): 928–39. DOI:10.1056/NEJMra052760. PMID 16943405. Research Blogging.
  3. Vernooij MW, Ikram MA, Tanghe HL, et al (November 2007). "Incidental findings on brain MRI in the general population". N. Engl. J. Med. 357 (18): 1821–8. DOI:10.1056/NEJMoa070972. PMID 17978290. Research Blogging.
  4. Wiebers DO, Whisnant JP, Huston J, et al (July 2003). "Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment". Lancet 362 (9378): 103–10. PMID 12867109[e]