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In pharmacology, indomethacin is "non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes."[1]


Initially, 25 mg orally two or three times per day. May increase the daily dosage by 25 mg or by 50 mg, if tolerated and required by symptoms, at weekly intervals as needed or a total daily dose of 150 mg to 200 mg is reached (Package insert).


  1. Anonymous (2015), Indomethacin (English). Medical Subject Headings. U.S. National Library of Medicine.

External links

The most up-to-date information about Indomethacin and other drugs can be found at the following sites.