Hyperglycemic hyperosmolar nonketotic coma

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Hyperglycemic hyperosmolar nonketotic coma is a complication of diabetes mellitus type 2.


Criteria for hospitalization, according to the American Diabetic Association, are:[1]

  • severe hyperglycemia (e.g., plasma glucose >600 mg/dl [>33.3 mmol/l]) and
  • elevated serum osmolality (e.g., >320 mOsm/kg [>320 mmol/kg])


  1. American Diabetes Association (2004). "Hospital admission guidelines for diabetes.". Diabetes Care 27 Suppl 1: S103. PMID 14693939[e]