Also called Hodgkin disease and Hodgkin's lymphoma, Hodgkin's disease is a malignant, but potentially curable, disease of the lymph nodes, spleen, and general lymphoid tissue.
- nodular sclerosis
- mixed cellularity
- lymphocyte depleted
- lymphocyte rich
- nodular lymphocyte predominant Hodgkin disease (NLPHD).
Classical and NLHPD are different clinical entities.
In the classical variant, giant usually multinucleate Hodgkin's and Reed-Sternberg cells, the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.
- Jaffe ES, Harris NL, Stein H, Vardiman JW, eds. World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press; 2001.
- Scott K Dessain, James L Spears, Athanassios Argiris (22 December 2009), "Hodgkin Disease: Overview", eMedicine