Framingham Heart Study

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In epidemiology, the Framingham Heart Study was a cohort study that started in 1948 for the objective of:[1]

"The objective of the Framingham Heart Study was to identify the common factors or characteristics that contribute to CVD by following its development over a long period of time in a large group of participants who had not yet developed overt symptoms of CVD or suffered a heart attack or stroke."

The study was sponsored by the National Heart, Lung, and Blood Institute of the National Institutes of Health.

Research that has emerged from the study includes:


  1. History of the Framingham Heart Study
  2. D'Agostino RB, Grundy S, Sullivan LM, Wilson P, CHD Risk Prediction Group (2001). "Validation of the Framingham coronary heart disease prediction scores: results of a multiple ethnic groups investigation.". JAMA 286 (2): 180-7. PMID 11448281[e] Review in: ACP J Club. 2002 Jan-Feb;136(1):36
  3. Wilson PW, D'Agostino RB, Levy D, Belanger AM, Silbershatz H, Kannel WB (1998). "Prediction of coronary heart disease using risk factor categories.". Circulation 97 (18): 1837-47. PMID 9603539[e]
  4. D'Agostino RB, Vasan RS, Pencina MJ, Wolf PA, Cobain M, Massaro JM et al. (2008). "General cardiovascular risk profile for use in primary care: the Framingham Heart Study.". Circulation 117 (6): 743-53. DOI:10.1161/CIRCULATIONAHA.107.699579. PMID 18212285. Research Blogging.