Fluconazole

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Fluconazole.

Fluconazole, IUPAC name 2-(2,4-difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol, is a synthetic triazole antifungal agent that is used to treat oropharyngeal (vaginal) candidiasis and cryptococcal meningitis in AIDS. Fluconazole interacts with the enzyme 14-α demethylase that converts lanosterol to ergosterol. Because ergosterol is an essential component of the fungal cell membrane, inhibition of ergosterol results in increased cellular permeability and cellular leakage.

Brand Names

  • Biocanol®
  • Biozolene®
  • Diflucan®
  • Elazor®
  • Flucazol®
  • Flucostat®
  • Flukezol®
  • Flunizol®
  • Flusol®
  • Pritenzol®
  • Triflucan®

External Links

The most up-to-date information about Fluconazole and other drugs can be found at the following sites.