Drug-induced liver injury

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In gastroenterology and pharmacology, drug-induced liver injury, also called drug-induced liver disease or drug-induced hepatoxocity is "injury to the liver that is associated with impaired liver function caused by exposure to a drug".[1] Common causes include antibiotics, anticonvulsants, and psychotropic drugs.[2]

Contents

Patterns of liver injury

Hepatocellular

Cholestatic

Mixed

References

  1. ↑ Navarro VJ, Senior JR (February 2006). Drug-related hepatotoxicity. N. Engl. J. Med. 354 (7): 731–9. DOI:10.1056/NEJMra052270. PMID 16481640.
  2. ↑ Chalasani N, Fontana RJ, Bonkovsky HL, et al (December 2008). Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States. Gastroenterology 135 (6): 1924–34, 1934.e1–4. DOI:10.1053/j.gastro.2008.09.011. PMID 18955056.

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