Cefoxitin

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cefoxitin
IUPAC name: see chemistry section
Synonyms:
Formula: C16H17N3O7S2

 Uses: antibiotic drug

 Properties: beta-lactam

 Hazards: see drug interactions

Mass (g/mol): CAS #:
427.4520 35607-66-0


Cefoxitin is a semi-synthetic, broad-spectrum cephalosporin type of antibiotic, derived from cephamycin C produced by Streptmyces lactamdurans. It is administered intravenously. It is sold under the brand names Mefoxin and Mefoxitin.

Mechanism of Action

Cephalosporin and penicilin-based antbacterial agents inhibit cell wall synthesis of bacteria by binding to penicilin-binding proteins in bacteria through an acylation reaction of the core beta-lactam structure with the cell's proteins.


Chemistry

The IUPAC name for cefoxitin is (6R,7S)-3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. It has chemical formula C16H17N3O7S2 and molecular mass of 427.4520 grams/mol. Its antibiotic properties are due to its core beta-lactam structure, which is common to all cephalosporins.

References

The most up-to-date information about Cefoxitin and other drugs can be found at the following sites.