Amprenavir

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Amprenavir structure.jpg
amprenavir
IUPAC name: see chemistry section
Synonyms: AMP, AMV, APV, VX-478
Formula: C25H35N3O6S

 Uses: HIV

 Properties: protease inhibitor

 Hazards: see drug interactions

Mass (g/mol): CAS #:
505.6269 161814-49-9



Amprenavir, also called AMP, AMV, APV and VX-478, is a protease inhibitor used to treat HIV infection. Protease inhibitors block HIV-1 protease, an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. Its IUPAC chemical name is [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3- hydroxy-1-phenylbutan-2-yl]carbamate.

Brand Names

  • Agenerase®
  • Prozei®
  • Vertex®

External Links

The most up-to-date information about Amprenavir and other drugs can be found at the following sites.