Amifostine

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Amifostine.png
amifostine
IUPAC name: see chemistry section
Synonyms:
Formula: C5H15N2O3PS

 Uses: radiation,chemotherapy

 Properties: radical scavenger

 Hazards: see side effects & drug interactions

Mass (g/mol): CAS #:
214.22


Amifostine is a cytoprotective agent that scavenges reactive oxygen species and other highly reactive free radicals. It is used to reduce the renal toxicity of cisplatin and to reduce the effects of radiation on normal tissue. It is a prodrug that becomes dephosphorylated by alkaline phosphatase into the active thiol form.

The most up-to-date information about Amifostine and other drugs can be found at the following sites.