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- {{Image|Tyrosine stick figure.jpg|right|150px|'''Tyrosine''', a common amino acid.}} ...rylation events are central to many [[cell-signalling]] pathways. Although tyrosine is [[hydrophobic]] and the side chain is mostly buried in proteins, it is o1 KB (170 words) - 09:00, 8 June 2009
- ...involved in [[Signal transduction|cell signaling]] pathways (this includes tyrosine kinases themselves), usually in a cascade of phosphorylation events in whic ...evel. In dividing cells, it is abundant. An extraordinarily high amount of tyrosine phosphorylation is also seen in cancer cells and in cases of inflammation d1 KB (162 words) - 20:16, 12 January 2009
- #REDIRECT [[Tyrosine kinase]]29 bytes (3 words) - 17:02, 20 December 2007
- 12 bytes (1 word) - 19:05, 17 January 2008
- 159 bytes (20 words) - 12:26, 6 July 2008
- 12 bytes (1 word) - 17:04, 20 December 2007
- {{r|tyrosine}}437 bytes (57 words) - 12:26, 6 July 2008
- ...adenosine triphosphate (ATP) to the hydroxyl oxygen atom on the amino acid tyrosine.213 bytes (30 words) - 23:42, 12 January 2009
- {{r|Receptor tyrosine kinase}} {{r|Leukocyte tyrosine kinase receptor||**}}2 KB (234 words) - 00:42, 13 January 2009
Page text matches
- ...adenosine triphosphate (ATP) to the hydroxyl oxygen atom on the amino acid tyrosine.213 bytes (30 words) - 23:42, 12 January 2009
- {{Image|Tyrosine stick figure.jpg|right|150px|'''Tyrosine''', a common amino acid.}} ...rylation events are central to many [[cell-signalling]] pathways. Although tyrosine is [[hydrophobic]] and the side chain is mostly buried in proteins, it is o1 KB (170 words) - 09:00, 8 June 2009
- ...involved in [[Signal transduction|cell signaling]] pathways (this includes tyrosine kinases themselves), usually in a cascade of phosphorylation events in whic ...evel. In dividing cells, it is abundant. An extraordinarily high amount of tyrosine phosphorylation is also seen in cancer cells and in cases of inflammation d1 KB (162 words) - 20:16, 12 January 2009
- ...hydrated and decarboxylated to provide phenylpyruvate. In the synthesis of tyrosine, this step is an oxidative decarboxylation reaction that leaves the hydroxy ...te to PHE TYR.jpg|left|450px|Conversion of chorismate to phenylalanine and tyrosine.}}952 bytes (128 words) - 06:33, 8 June 2009
- {{r|Receptor tyrosine kinase}} {{r|Leukocyte tyrosine kinase receptor||**}}2 KB (234 words) - 00:42, 13 January 2009
- It is also known as Peptide Tyrosine Tyrosine, or Pancreatic Peptide YY3-36.321 bytes (52 words) - 09:52, 28 November 2013
- #REDIRECT [[Tyrosine kinase]]29 bytes (3 words) - 17:02, 20 December 2007
- A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number o162 bytes (21 words) - 08:14, 30 September 2009
- A family of intracellular tyrosine kinases that participate in the signaling cascade of cytokines by associati182 bytes (23 words) - 13:06, 17 November 2011
- ...and [[hormone]]s, chemically ortho-dihydroxyphenylalkylamines derived from tyrosine, with important members including [[epinephrine]], [[norepinephrine]], and205 bytes (21 words) - 19:45, 19 May 2010
- ...precursor for the biosynthesis of the [[amino acid]]s [[phenylalanine]], [[tyrosine]] and [[tryptophan]].167 bytes (20 words) - 14:42, 7 July 2008
- (HGFR, MET or c-MET) A receptor tyrosine kinase that is essential for embryonic development and wound healing; is al172 bytes (24 words) - 01:06, 13 January 2009
- ...tein]]s. It is one of four [[aromatic]] amino acids with [[histidine]], [[tyrosine]] and [[tryptophan]]. It is very [[hydrophobic]] is found almost exclusive ...ted and decarboxylated to provide [[phenylpyruvate]]. In the synthesis of tyrosine, this step is an oxidative decarboxylation reaction that leaves the hydroxy2 KB (209 words) - 08:43, 8 June 2009
- *[[Tyrosine kinase]] *[[Tyrosine phosphorylase]]969 bytes (78 words) - 23:28, 20 February 2010
- ...a class of biologically active substances, derived from the amino acid, [[tyrosine]]. Chemically, they are ortho-dihydroxyphenylalkylamines.325 bytes (35 words) - 13:59, 17 June 2009
- ...se B (PKB) family or Akt is an important downstream signaling component of tyrosine kinase growth factor and G-coupled receptors. Akt/PKB is activated by phosp304 bytes (43 words) - 02:10, 16 May 2009
- ...4734">{{cite journal |author=Robinson DR, Wu YM, Lin SF |title=The protein tyrosine kinase family of the human genome |journal=Oncogene |volume=19 |issue=49 |p2 KB (273 words) - 11:27, 4 May 2010
- ...signed to limit the intake of phenylalanine, as well as supplementing with tyrosine, and can reduce the severity of the symptoms allowing those with the diseas1 KB (218 words) - 22:30, 25 September 2008
- {{r|tyrosine}}509 bytes (57 words) - 00:12, 8 July 2008
- ...s one of the four [[aromatic]] amino acids along with [[phenylalanine]], [[tyrosine]] and [[tryptophan]]. At physioligical pH, histidine is usually protonated476 bytes (70 words) - 08:13, 8 June 2009
- {{r|tyrosine}}418 bytes (55 words) - 12:14, 6 July 2008
- {{r|tyrosine}}437 bytes (57 words) - 12:15, 6 July 2008
- {{r|tyrosine}}437 bytes (57 words) - 12:15, 6 July 2008
- {{r|tyrosine}}440 bytes (57 words) - 00:11, 8 July 2008
- {{r|tyrosine}}437 bytes (57 words) - 12:17, 6 July 2008
- {{r|tyrosine}}437 bytes (57 words) - 12:18, 6 July 2008
- {{r|tyrosine}}437 bytes (57 words) - 12:19, 6 July 2008
- {{r|tyrosine}}437 bytes (57 words) - 12:19, 6 July 2008
- {{r|tyrosine}}437 bytes (57 words) - 12:08, 6 July 2008
- {{r|tyrosine}}437 bytes (57 words) - 12:20, 6 July 2008
- {{r|tyrosine}}436 bytes (57 words) - 12:09, 6 July 2008
- {{r|tyrosine}}437 bytes (57 words) - 12:22, 6 July 2008
- {{r|tyrosine}}437 bytes (57 words) - 12:11, 6 July 2008
- {{r|tyrosine}}437 bytes (57 words) - 12:23, 6 July 2008
- {{r|tyrosine}}437 bytes (57 words) - 12:12, 6 July 2008
- {{r|tyrosine}}437 bytes (57 words) - 12:13, 6 July 2008
- {{r|tyrosine}}437 bytes (57 words) - 12:26, 6 July 2008
- {{r|tyrosine}}473 bytes (60 words) - 13:47, 5 August 2010
- {{r|Tyrosine}}461 bytes (59 words) - 11:50, 11 January 2010
- ...OH, it is subject to [[phosphorylation]] by [[kinases]]. [[Serine]] and [[tyrosine]] are the only other amino acids with hydroxyl groups on their side chains.586 bytes (91 words) - 08:59, 8 June 2009
- ...four [[aromatic]] amino acids with [[histidine]], [[phenylalanine]] and [[tyrosine]]. It is the most [[hydrophobic]] of the amino acids, and most well-folded781 bytes (112 words) - 13:48, 5 August 2010
- {{r|Tyrosine}}1,019 bytes (130 words) - 18:38, 11 January 2010
- {{r|Tyrosine}}1 KB (135 words) - 17:20, 11 January 2010
- '''Hepatocyte growth factor receptor''' (HGFR) is a [[receptor tyrosine kinase]] that is essential for embryonic development and wound healing. It908 bytes (127 words) - 01:01, 13 January 2009
- {{r|Tyrosine kinase}}1 KB (147 words) - 07:44, 8 January 2010
- {{r|Tyrosine}}1 KB (163 words) - 09:18, 6 March 2024
- {{r|tyrosine}}1 KB (154 words) - 00:11, 8 July 2008
- ...us kinases''', also known as JAK kinases, are "a family of intracellular [[tyrosine kinase]]s that participate in the signaling cascade of cytokines by associa1 KB (190 words) - 20:53, 22 August 2010
- ...ause it is one of the three amino acids, together with [[threonine]] and [[tyrosine]], that contain a [[hydroxyl]] group (OH) on the side chain. It can be thou1 KB (181 words) - 08:52, 8 June 2009
- ...The binding of ligand to the receptor causes activation of its intrinsic [[tyrosine kinase]] activity and rapid internalization of the receptor-ligand complex1 KB (208 words) - 07:56, 1 May 2010
- :From [[phenylalanine]] and [[tyrosine]]2 KB (214 words) - 01:02, 23 September 2008
- {{r|Tyrosine}}2 KB (265 words) - 10:53, 11 January 2010
- ...-2''', '''HER2/neu''') is a [[cell surface receptor]] that is a "[[protein-tyrosine kinase receptor]] that is found to be overexpressed in a significant number2 KB (308 words) - 06:03, 16 July 2010
- e.g., the two protons ortho to hydroxy group in tyrosine are chemically equivalent but they are not magnetically equivalent.2 KB (349 words) - 20:39, 19 February 2010
- |[[tyrosine|TYR]]2 KB (351 words) - 14:30, 19 June 2008
- ...+</sup> level. It also inhibits [[adenylate cyclase]] and activate various tyrosine kinases. Effects mediated by the AT<sub>1</sub> receptor include vasoconstr3 KB (321 words) - 13:33, 15 June 2008
- ...pathway) or by [[transmembrane receptor]]s with intrinsic or associated [[tyrosine kinase]] activity. *PLC-γ is activated by [[receptor tyrosine kinase]]s.6 KB (929 words) - 15:37, 12 November 2007
- {{r|Tyrosine}}4 KB (486 words) - 19:46, 11 January 2010
- :*[[Tyrosine]] (Tyr, Y)3 KB (443 words) - 21:24, 16 February 2010
- : ''From [[phenylalanine]] and [[tyrosine]] ([[catecholamines]], in the order of their synthesis):'' ...ibitor, hence potentiating its effect. [[AMPT]] prevents the conversion of tyrosine to [[L-DOPA]], the precursor to dopamine; [[reserpine]] prevents dopamine s10 KB (1,308 words) - 17:09, 21 March 2024
- ...]], [[dopamine]]. They are derived from the non-essential [[amino acid]] [[tyrosine]] which is found in casein in milk and cheese. ...messengers epinephrine, norepinephrine, and dopamine are synthesized from tyrosine by a common biosynthetic pathway."<ref name="title">{{MeSH|Receptors, Catec12 KB (1,572 words) - 08:41, 15 July 2010
- ...nts are shown to have dramatically increased levels of 2 cytosolic protein tyrosine phosphatases that contain src-homology 2 (SH2): SHP-1 and SHP-2. One hypoth4 KB (548 words) - 18:07, 30 July 2010
- ...ently bound to a protein termed [[glycogenin]] as a β-linkage to a surface tyrosine residue. [[Glycogenin]] is a glycosyltransferase and occurs as a dimer in t5 KB (834 words) - 14:45, 26 September 2007
- ...c Polypeptide (PP)-fold family, namely PP itself and also peptide tyrosine-tyrosine (PYY), the first gut hormone shown to have appetite-inhibiting properties.13 KB (1,840 words) - 06:29, 13 November 2009
- ...expressed on the surface of target cells (thoufgh some act via receptor [[tyrosine kinase]]s). There can be several different receptors through which any one8 KB (1,118 words) - 17:09, 21 March 2024
- ...ic encephalopathy among patients with an abnormal and normal serum 3-nitro-tyrosine above 14 nM were 75.0% and 4.0%, respectively. <ref name="pmid21483460"/>20 KB (2,703 words) - 21:02, 31 October 2011
- ...kaptonuria]]</td><td>homogentisic acid oxidase</td><td>Stops catabolism of tyrosine to (via homogentisic acid) [[Maleylacetoacetic acid]]</td><td></td><td></td12 KB (1,863 words) - 14:08, 5 November 2007
- ''[[Peptide tyrosine tyrosine]]'' (PYY) is a peptide belonging to the [[neuropeptide Y]] (NPY) family. PY18 KB (2,561 words) - 10:26, 24 July 2011
- ...wth factor]] that activates the Axl [[receptor (biochemistry)|receptor]] [[tyrosine kinase]] and stimulates cell proliferation or prevents [[apoptosis]] in som9 KB (1,333 words) - 07:35, 9 June 2009
- #[[Amine]]-derived hormones are derivatives of the [[amino acid]]s [[tyrosine]] and [[tryptophan]]. Examples are the [[catecholamine]]s ([[dopamine]], [[10 KB (1,501 words) - 06:37, 9 June 2009
- Tyrinosinase is an enzyme that acts on the amino acid tyrosine in metabolism, and is required for melanin production in mammals. If this10 KB (1,623 words) - 21:25, 1 November 2009
- ...[[catecholamine]] [[neurotransmitter]]s in the brain. It is derived from [[tyrosine]] and is the precursor to norepinephrine and epinephrine. Dopamine is a maj11 KB (1,475 words) - 02:04, 22 August 2010
- ...sequences between the "fused in glioblastoma" (fig) gene and the receptor tyrosine kinase "ros", producing a fusion protein (FIG-ROS). The abnormal FIG-ROS fu13 KB (2,019 words) - 00:14, 11 November 2007
- ...of nine [[amino acid]]s (a nonapeptide). The sequence is [[cysteine]] - [[tyrosine]] - [[isoleucine]] - [[glutamine]] - [[asparagine]] - [[cysteine]] - [[prol ...e of oxytocin is very similar to that of [[vasopressin]] ([[cysteine]] - [[tyrosine]] - <u>[[phenylalanine]]</u> - [[glutamine]] - [[asparagine]] - [[cysteine]24 KB (3,372 words) - 17:09, 21 March 2024
- ...of nine [[amino acid]]s (a nonapeptide). The sequence is [[cysteine]] - [[tyrosine]] - [[isoleucine]] - [[glutamine]] - [[asparagine]] - [[cysteine]] - [[prol ...e of oxytocin is very similar to that of [[vasopressin]] ([[cysteine]] - [[tyrosine]] - <u>[[phenylalanine]]</u> - [[glutamine]] - [[asparagine]] - [[cysteine]24 KB (3,415 words) - 17:09, 21 March 2024
- ...stimulation of the receptor, is a cause for the disease. Inhibiting the [[tyrosine kinase]] receptor with [[imatinib]] (see below) may reduce the symptoms of13 KB (1,802 words) - 09:02, 1 March 2024
- ...ivated by cleavage). The amino acid sequence of AVP is [[cysteine|Cys]]-[[tyrosine|Tyr]]-[[Phenylalanine|Phe]]-[[glutamine|Gln]]-[[asparagine|Asn]]-[[Cysteine15 KB (1,951 words) - 10:35, 8 August 2011
- ...for a receptor without the intraceullar C terminal, which is necessary for tyrosine kinase activation. Only one family have been found to have a leptin recept21 KB (3,145 words) - 15:26, 25 February 2023
- * [[Tyrosine]] — C<sub>9</sub>O<sub>3</sub>H<sub>11</sub>N30 KB (3,104 words) - 14:21, 8 March 2024
- * [[Tyrosine]]25 KB (3,396 words) - 13:29, 2 April 2024
- ...the enzyme that catalyzes the decarboxylation of p-hydroxyphenylacetate (a tyrosine degradation product) to p-crysol, a compound that stunts bacterial growth.46 KB (6,252 words) - 17:10, 31 October 2013
- ...15800324}}</ref> A small pilot study suggested possible benefit from the [[tyrosine kinase]] inhibitor [[erlotinib]] in patients with advanced cholangiocarcino46 KB (6,423 words) - 06:04, 5 April 2024
- ...protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells] G. Schuetz et al (2004) Journal of Cell Bio49 KB (7,285 words) - 04:27, 20 January 2011
- Tyrosine hydroxylase is rate limiting in the synthesis of all catecholamines ([[dopa87 KB (12,868 words) - 00:29, 15 September 2013