In medicine, glomerulonephritis, also called Bright's Disease, is "inflammation of the renal glomeruli (kidney glomerulus) that can be classified by the type of glomerular injuries including antibody deposition, complement activation, cellular proliferation, and glomerulosclerosis. These structural and functional abnormalities usually lead to hematuria; proteinuria; hypertension; and renal insufficiency.".
Etiology and Pathology
Glomerulonephritis is "characterized by intraglomerular inflammation and cellular proliferation associated with hematuria. This definition excludes several important nonproliferative or sclerosing glomerulopathies such as membranous glomerulopathy, focal segmental glomerulosclerosis, and diabetic nephropathy."
Hematuria in glomerulonephritis "is typified by the presence of dysmorphic red cells or red-cell casts in the urine"  However, these findeing cannot differentiate proliferative from nonproliferative glomerulopathies.
- Anonymous (2021), Glomerulonephritis (English). Medical Subject Headings. U.S. National Library of Medicine.
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