- Titan (mythology) : In Greek mythology, according to Elizabeth Vandiver, a Classics scholar, they were gods who were the offspring or children of the primordial gods Gaia and Ouranos, and who preceded the Olympians such as Zeus and Hera and Apollo and Athena and others. They included: Oceanus, Hyperion, Coeus, Cronus, Crius, Iapetus, Mnemosyne, Tethys, Theia, Phoebe, Rhea,Themis, Eos, Helios, Selene, Leto, Asteria, Atlas, Prometheus (who helped mankind), Epimetheus, Menoetius, Astraeus, Pallas, and Perses.
- Titan (moon) : Moon of Saturn, the second-largest moon in the Solar System
- HGM-25A Titan I : First-generation U.S. intercontinental ballistic missile
- UGM-27 Titan II : A second-generation U.S. intercontinental ballistic missile able to lift unusually large warheads, and used as a space launch vehicle after military retirement. As an ICBM, it carried the largest warhead of any U.S. missile
- Titan III : Interim U.S. space launch vehicle derived from the UGM-27 Titan II
- Titan IV : Operational family of U.S. heavy space launch vehicles
- Tennessee Titans : National Football League professional American football team in Nashville, Tennessee
- Titanium : A chemical element, having the chemical symbol Ti, and atomic number (the number of protons) 22.; engineering applications as a lightweight and strong metal