Nocturnal leg cramps
Jump to navigation
Jump to search
In medicine, nocturnal leg cramps are a sleep-wake transition disorder which is a type of parasomia.[1]
Various medications may cause nocturnal leg cramps:[2]
- Diuretics, especially potassium sparing
- Long acting adrenergic beta-agonists (LABAs)
- Hydroxymethylglutaryl-coenzyme A reductase inhibitors (statins)
Treatment
Clinical practice guidelines direct treatment. Quinine should be avoided.[3] However, some patients probably benefit from quinine.[4]
Muscle stretching may help.[5]
References
- ↑ Anonymous (2023), Sleep-wake transition disorders (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Garrison, Scott R.; Colin R. Dormuth, Richard L. Morrow, Greg A. Carney, Karim M. Khan (2011-12-12). "Nocturnal Leg Cramps and Prescription Use That Precedes Them: A Sequence Symmetry Analysis". Arch Intern Med: archinternmed.2011.1029. DOI:10.1001/archinternmed.2011.1029. Retrieved on 2011-12-13. Research Blogging.
- ↑ Katzberg, Hans D.; Ahmir H. Khan, Yuen T. So (2010-02-23). "Assessment: Symptomatic treatment for muscle cramps (an evidence-based review): Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology". Neurology 74 (8): 691-696. DOI:10.1212/WNL.0b013e3181d0ccca. PMID 20177124. Retrieved on 2010-02-23. Research Blogging.
- ↑ Woodfield R, Goodyear-Smith F, Arroll B (2005). "N-of-1 trials of quinine efficacy in skeletal muscle cramps of the leg.". Br J Gen Pract 55 (512): 181-5. PMID 15808032. PMC PMC1463087.
- ↑ Hallegraeff JM, van der Schans CP, de Ruiter R, de Greef MH (2012). "Stretching before sleep reduces the frequency and severity of nocturnal leg cramps in older adults: a randomised trial.". J Physiother 58 (1): 17-22. DOI:10.1016/S1836-9553(12)70068-1. PMID 22341378. Research Blogging.