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- 3-hydroxy-3-methyl-glutaryl CoA : A chemical precursor of mevalonate and, therefore, cholesterol.
- Anticholesteremic agent : Substance that promote a reduction of blood cholesterol levels.
- Antilipemic agent : Medications for the treatment of hypercholesterolemia and hypertriglyceridemia.
- Atherosclerosis : Thickening and loss of elasticity of the walls of medium and large muscular arteries with lesions in the innermost layer.
- Atorvastatin : Sold as Lipitor®, a type II statin used to treat high cholesterol (hypercholesterolemia),
- Cerivastatin : A type II statin formerly used to treat high cholesterol levels (hypercholesterolemia).
- Cholesterol : Principal sterol of all higher animals.
- Clinical practice guideline : Document with the aim of guiding decisions and criteria regarding diagnosis, management, and treatment in specific areas of healthcare.
- Coronary heart disease : Disease of the heart that involves narrowing of the coronary arteries.
- Delavirdine : An antiviral drug and reverse transcriptase inhibitor (nNRTI) specific for HIV-1.
- Diabetes mellitus type 2 : Medical condition characterised by glucose intolerance and hyperglycemia
- Dietary fiber : Remnants of plant cell walls that are resistant to digestion by the alimentary enzymes of man, comprising various polysaccharides and lignins.
- Digital object identifier : Unique label for a computer readable object that can be found on the internet, usually used in academic journals.
- Dyslipidemia : Abnormal lipid serum levels, such as high total cholesterol or triglycerides, low HDL or high LDL cholesterol.
- Ezetimibe : An anti-hyperlipidemic medication used to lower cholesterol levels.
- Fish oil : Oils high in unsaturated fats extracted from the bodies of fish or fish parts, especially the livers.
- Fluvastatin : Fluorophenyl-based statin, HMG-CoA reductase inhibitor, for reduction of cholesterol, triglycerides and apo B.
- Food and Drug Administration : The agency of the United States Department of Health and Human Services responsible for regulating food, dietary supplements, drugs, biological medical products, blood products, medical devices, radiation-emitting devices, veterinary products, and cosmetics.
- Gemfibrozil : A drug that lowers serum triglyceride levels, with variable effects on cholesterol.
- Hydroxymethylglutaryl-coenzyme A reductase inhibitor : HMG-CoA reductase inhibitors which reduce 3-hydroxy-3-methyl-glutaryl CoA and lower cholesterol synthesis.
- Imidacloprid : A chloronicotinyl insecticide that acts on the nicotinic acetylcholine receptor.
- Lipid : Group of organic compounds, including the fats, oils, waxes, sterols, and triglycerides, that are insoluble in water but soluble in nonpolar organic solvents, and together with carbohydrates and proteins constitute the principal structural material of living cells.
- Lovastatin : Type I statin and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor used to treat hypercholesterolemia.
- Mevalonate : A key chemical precursor in the biosynthesis of cholesterol.
- Mevastatin : Statin drug used to treat hypercholesterolemia by inhibiting the enzyme HMG-CoA reductase.
- National Institute for Health and Clinical Excellence : Part of the National Health Service, in the United Kingdom.
- Pravastatin : Type I Statin used to treat hypercholesterolemia.
- Rhabdomyolysis : Acute, fulminant, potentially fatal disease that destroys skeletal muscle and is often accompanied by the excretion of myoglobin in the urine.
- Rosuvastatin : A type II statin, marketed as Crestor®, used to treat high cholesterol levels.
- Simvastatin : A semisynthetic lipid-lowering drug derived from a compound produced by a mold of the genus Aspergillus and administered orally to lower a high cholesterol level in the blood by inhibiting the action of an enzyme catalyzing the synthesis of cholesterol.
- Stroke : A sudden loss of brain function due to interrupted blood supply.
- Tacrolimus : A macrolide with a number of immunosuppressant applications in medicine, originally introduced to prevent rejection of transplanted organs
- Thrombolysis in Myocardial Infarction (TIMI) risk score : The Thrombolysis in Myocardial Infarction (TIMI) Risk Score is a clinical prediction rule that can predict the likelihood of morbidity in patients with unstable angina or Non-ST segment elevation myocardial infarction (NSTEMI).
- Vascular disease : Pathological processes involving any of the blood vessels in the cardiac or peripheral circulation. They include diseases of arteries; veins; and rest of the vasculature system in the body.