Chemistry and Mechanism of Action
The chemical name of anacetrapib, distributed by Merck, is 2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl]-4-methyl-1,3-oxazolidin-2-one. It has a formula weight of 637.51 g/mol and its CAS registration number is 875446-37-0. Anacetrapib is an inhibitor of cholesteryl ester transfer protein (CETP), a key protein involved in reverse cholesterol transport, and its use increases high-density lipoprotein cholesterol (HDL). Other CETP inhibitors include dalcetrapib and torcetrapib. ,
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