|Hazards:||see drug interactions|
Amprenavir, also called AMP, AMV, APV and VX-478, is a protease inhibitor used to treat HIV infection. Protease inhibitors block HIV-1 protease, an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs. Its IUPAC chemical name is [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3- hydroxy-1-phenylbutan-2-yl]carbamate.
The most up-to-date information about Amprenavir and other drugs can be found at the following sites.