Kinins

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Kinins are a "generic term used to describe a group of polypeptides with related chemical structures and pharmacological properties that are widely distributed in nature. These peptides are autacoids that act locally to produce pain, vasodilatation, increased vascular permeability, and the synthesis of prostaglandins. Thus, they comprise a subset of the large number of mediators that contribute to the inflammatory response. (From Goodman and Gilman's The Pharmacologic Basis of Therapeutics, 8th ed, p588)".[1][2]

Contents

Classification

Bradykinin

For more information, see: Bradykinin.


Kininogens

Tachykinins

These include the neurotransmitter Substance P which transmits pain.

Urotensins

Found in bony fishes.[3]

References

  1. ↑ Gilman, Alfred; Goodman, Louis Sanford (1990). Goodman and Gilman's The Pharmacological Basis of Therapeutics. New York: Pergamon Press, 588. ISBN 0-08-040296-8. 
  2. ↑ Anonymous, (2009) Kinins (English). Medical Subject Headings. U.S. National Library of Medicine.
  3. ↑ Anonymous, (2009) Urotensins (English). Medical Subject Headings. U.S. National Library of Medicine.
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