Pregabalin

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Pregabalin and gabapentin are structurally similar to GABA.

Pregabalin is structurally similar to gabapentin. It is also similar to the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), and although it does not act on GABA receptors, it may increase the "density of GABA transporter protein and increases the rate of functional GABA transport".^[1] It is approved by the FDA for neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia adjunctive therapy for adult patients with partial onset seizures, and fibromyalgia.^[1]

chemistry

The IUPAC chemical name for pregabalin is (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid. Its chemical formula is C₈H₁₇NO₂ giving it a molecular mass of 159.23 g/mol. It is both an amine and a carboxylic acid.

External links

The most up-to-date information about Pregabalin and other drugs can be found at the following sites.

• Pregabalin - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
• Pregabalin - Drug information for consumers from MedMaster (U.S. National Library of Medicine).
• Pregabalin - Detailed information from DrugBank.

References

1. ↑ ^1.0 1.1 The most up-to-date information about Pregabalin and other drugs can be found at the following sites.
   • Pregabalin - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
   • Pregabalin - Drug information for consumers from MedMaster (U.S. National Library of Medicine).
   • Pregabalin - Detailed information from DrugBank.