- BigCleanup deleted items
- [[image:Platelet_blood_bag.jpg|thumb|A 250 ml bag of newly collected platelets.]]
Plan for article
I suggest that this article be written in plain enough language so that any literate English speaking person could read through it, and even though all of it would not be understood, she or he would have the basic idea of what platelets are, where they come from (megokaryocytes- bone marrow etc), how they have a finite useful circulating time, how they can call an immediate halt to bleeding, how they are important in thrombus formation, and why thrombus formation can be a helpful stop to bleeding, or a pathological stage in DIC, or cause infarction.
Enough must be said about the physiology of platelets so that the article is also useful for those interested in the molecular biology of hemostasis, bringing in phospholipases etc. At this time, the first Citizendium edits, I am approaching the subject from editing Snake venom. Nancy Sculerati MD
from platelets article redirect
Nancy Sculerati has already built an extensive "Platelet" page that I didn't notice before building this "Platelets" page. There was a link on the "Megakaryocyte" page to "Platelets" that I followed; the link now goes to Nancy's page. -Barney (Talk)
Information from the Platelets article move-
- Platelets (thrombocytes) are normal constituents of blood that are essential for normal hemostasis. They are fragments of megakaryocyte cytoplasm that arise in the bone marrow at a rate of ~1011 per day to maintain a normal concentration of 2 to 3 x 108/mL. Platelets localize to sites of vascular injury to form a plug, which slows or stops bleeding.
References consulted for article (running list)
1. Edward F. Plow, Charles S. Abrams: Chapter 106 –THE MOLECULAR BASIS FOR PLATELET FUNCTION in Hoffman: Hematology: Basic Principles and Practice, 4th ed., Copyright © 2005 Churchill Livingstone, An Imprint of Elsevier