Rimantadine

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rimantadine
IUPAC name: 1-(1-adamantyl)ethanamine Synonyms: Flumadine®, Levofloxacin HCl®, Rimantadine HCL®. Formula: C12H21N
Uses:	Influenza A
Properties:	adamantane derivative
Hazards:	see drug interactions
Mass (g/mol): CAS #: 179.3018 13392-28-4

Rimantadine is an RNA synthesis inhibitor that is used as an antiviral drug in the prophylaxis and treatment of influenza A that is based on the structure of adamantane and is similar to the drug amantadine. It is effective against all antigenic subtypes of influenza A but is not effective against influenza B. The mechanism of action for this drug is not definitively known but it may hinder the uncoating of the virus.

Chemistry

Its IUPAC chemical name is 1-(1-adamantyl)ethanamine and it has chemical formula C₁₂H₂₁N. It is sold under the brand names Flumadine®, Levofloxacin hydrochloride® and Rimantadine HCL®. It is a structural analog of the chemical adamantane.

External links

The most up-to-date information about Rimantadine and other drugs can be found at the following sites.

• Rimantadine - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
• Rimantadine - Drug information for consumers from MedMaster (U.S. National Library of Medicine).
• Rimantadine - Detailed information from DrugBank.