Pyelonephritis

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In medicine, pyelonephritis is a form of urinary tract infection that is "inflammation of the kidney involving the renal parenchyma (the nephrons); kidney pelvis; and kidney calices. It is characterized by abdominal pain; fever; nausea; vomiting; and occasionally diarrhea."[1]

Treatment

Antibiotics may be given by mouth or intravenously for adults[2] or children[3].

In children, 3 versus 8 days of intravenous antibiotics had similar outcomes.[4]

Prognosis

About 15% of patients persist with fever after 48 hours of antibiotics.[5]

References

  1. Anonymous, (2009) Pyelonephritis (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. Pohl A (2007). Modes of administration of antibiotics for symptomatic severe urinary tract infections. Cochrane Database Syst Rev (4): CD003237. DOI:10.1002/14651858.CD003237.pub2. PMID 17943784.
  3. Montini G, Toffolo A, Zucchetta P, et al (August 2007). Antibiotic treatment for pyelonephritis in children: multicentre randomised controlled non-inferiority trial. BMJ 335 (7616): 386. DOI:10.1136/bmj.39244.692442.55. PMID 17611232. PMC 1955287.
  4. Bouissou F, Munzer C, Decramer S, et al (March 2008). Prospective, randomized trial comparing short and long intravenous antibiotic treatment of acute pyelonephritis in children: dimercaptosuccinic acid scintigraphic evaluation at 9 months. Pediatrics 121 (3): e553–60. DOI:10.1542/peds.2006-3632. PMID 18267977.
  5. Grover SA, Komaroff AL, Weisberg M, Cook EF, Goldman L (1987). "The characteristics and hospital course of patients admitted for presumed acute pyelonephritis". J Gen Intern Med 2 (1): 5–10. PMID 3543268.
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