NOTICE: Citizendium is still being set up on its newer server, treat as a beta for now; please see here for more.
Citizendium - a community developing a quality comprehensive compendium of knowledge, online and free. Click here to join and contribute—free
CZ thanks our previous donors. Donate here. Treasurer's Financial Report -- Thanks to our content contributors. --


From Citizendium, the Citizens' Compendium
Revision as of 16:10, 25 January 2008 by David E. Volk (Talk | contribs) (brand names)

Jump to: navigation, search
This article is a stub and thus not approved.
Main Article
Related Articles  [?]
Bibliography  [?]
External Links  [?]
Citable Version  [?]
This editable Main Article is under development and not meant to be cited; by editing it you can help to improve it towards a future approved, citable version. These unapproved articles are subject to a disclaimer.
(CC) Image: David E. Volk

Gemfibrozil, or 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid), is drug that lowers serum triglyceride levels, with variable effects on cholesterol. The VLDL fraction is preferentially lowered and LDL less so. The HDL subfractions HDL2 and HDL3, and apolipoproteins A-I and A-II, are increased. Gemfibrozil is a fibric acid antilipemic drug similar to clofibrate that is used to treat hyperlipoproteinemia and supplimental therapy for type IIb hypercholesterolemia. Gemfibrozil increases lipoprotein triglyceride lipolysis by increasing the activity of extrahepatic lipoprotein lipase. Chylomicrons are degraded, VLDLs are converted to LDLs, and LDLs are converted to HDL.

Brand Names

  • Apo-Gemfibrozil
  • Bolutol
  • Cholespid
  • Decrelip
  • Fibratol
  • Fibrocit
  • Gemfibril
  • Gemfibromax
  • Gemlipid
  • Gen-Fibro
  • Genlip
  • Gevilon
  • Hipolixan
  • Jezil
  • Lipozid
  • Lipur
  • Lopid
  • Novo-Gemfibrozil
  • Nu-Gemfibrozil

External Links