Fludrocortisone

From Citizendium, the Citizens' Compendium

	Main Article	Talk	Related Articles  [?]	Bibliography  [?]	External Links  [?]
	This is a draft article, under development and not meant to be cited but you can help to improve it. These unapproved articles are subject to a disclaimer. [edit intro]

Fludrocortisone has at least 50^[1][2] times more mineralocorticoid activity than hydrocortisone.

Fludrocortisone one mg orally per day is equivalent to aldosterone 4 mg intramuscularly every six hours.^[3]

References

1. ↑ Goldfien A, Laidlaw JC, Haydar NA, Renold AE, Thorn GW (March 1955). "Fluorohydrocortisone and chlorohydrocortisone, highly potent derivatives of compound F". N. Engl. J. Med. 252 (11): 415–21. PMID 14356353.
2. ↑ Thorn GW, Renold AE, Morse WI, Goldfien A, Reddy WJ (November 1955). "Highly potent adrenal cortical steroids: structure and biologic activity". Ann. Intern. Med. 43 (5): 979–1000. PMID 13268992.
3. ↑ Thorn GW, Sheppard RH, Morse WI, Reddy WJ, Beigelman PM, Renold AE (May 1955). Comparative action of aldosterone and 9-alpha-fluorohydrocortisone in man. Ann. N. Y. Acad. Sci. 61 (2): 609–19. PMID 13249284.