Human Immunodeficiency Virus Type 2: Difference between revisions
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In [[virology]], '''Human Immunodeficiency Virus Type 2''' ('''HIV-2''') is an "[[Human Immunodeficiency Virus|HIV]] species related to [[Human Immunodeficiency Virus Type 1|HIV-1]] but carrying different antigenic components and with differing nucleic acid composition. It shares serologic reactivity and sequence homology with the simian [[Lentivirus]] [[simian immunodeficiency virus]] and infects only T4-lymphocytes expressing the [[CD4 antigen|CD4]] phenotypic marker."<ref>{{MeSH | {{subpages}} | ||
In [[virology]], '''Human Immunodeficiency Virus Type 2''' ('''HIV-2''') is an "[[Human Immunodeficiency Virus|HIV]] [[species]] related to [[Human Immunodeficiency Virus Type 1|HIV-1]] but carrying different antigenic components and with differing [[nucleic acid]] composition. It shares serologic reactivity and sequence [[homology]] with the simian [[Lentivirus]] [[simian immunodeficiency virus]] and infects only T4-lymphocytes expressing the [[CD4 antigen|CD4]] phenotypic marker."<ref>{{MeSH}}</ref> | |||
HIV-2 is thought to have originated by zoonotic transfer to humans from [[simian immunodeficiency virus]]<sub>sooty mangabey</sub> (''[[Cercocebus atys]]'') in the [[Guinea-Bissau]] region of coastal [[West Africa]] during their independence war (1963–1974). <ref name="pmid12743376">{{cite journal| author=Lemey P, Pybus OG, Wang B, Saksena NK, Salemi M, Vandamme AM| title=Tracing the origin and history of the HIV-2 epidemic. | journal=Proc Natl Acad Sci U S A | year= 2003 | volume= 100 | issue= 11 | pages= 6588-92 | pmid=12743376 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&retmode=ref&cmd=prlinks&id=12743376 | doi=10.1073/pnas.0936469100 | pmc=PMC164491 }} </ref> | |||
==References== | ==References== | ||
<references/> | <references/> | ||
Latest revision as of 09:00, 6 October 2010
In virology, Human Immunodeficiency Virus Type 2 (HIV-2) is an "HIV species related to HIV-1 but carrying different antigenic components and with differing nucleic acid composition. It shares serologic reactivity and sequence homology with the simian Lentivirus simian immunodeficiency virus and infects only T4-lymphocytes expressing the CD4 phenotypic marker."[1]
HIV-2 is thought to have originated by zoonotic transfer to humans from simian immunodeficiency virussooty mangabey (Cercocebus atys) in the Guinea-Bissau region of coastal West Africa during their independence war (1963–1974). [2]
References
- ↑ Anonymous (2024), Human Immunodeficiency Virus Type 2 (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Lemey P, Pybus OG, Wang B, Saksena NK, Salemi M, Vandamme AM (2003). "Tracing the origin and history of the HIV-2 epidemic.". Proc Natl Acad Sci U S A 100 (11): 6588-92. DOI:10.1073/pnas.0936469100. PMID 12743376. PMC PMC164491. Research Blogging.