Erythrocyte transfusion: Difference between revisions

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==Adverse effects==
==Adverse effects==
{{main|Transfusion reaction}}
{{main|Transfusion reaction}}
===Immunologic reactions===
* '''Febrile nonhemolytic transfusion reactions (FNHTR)''' due to destruction of incompatible donor white blood cells
* '''Hemolytic reactions''' due to [[blood group incompatibility]] is "mismatch between donor and recipient blood. [[Antibody|Antibodies]] present in the recipient's serum are directed against [[antigen]]s in the donor product. Such a mismatch may result in a transfusion reaction in which, for example, donor blood is hemolyzed."<ref>{{MeSH|Blood group incompatibility}}</ref>
** Acute hemolytic transfusion reactions due to ABO incompatibility
** Delayed hemolytic transfusion reactions
* '''Allergic reactions'''
** Anaphylactic transfusion reactions may occur, especially in patients with IgA-deficiency.
** Urticaria may occur due to the recipient's IgE reacting to antigens from the donor.
* '''Posttransfusion purpura (PTP)''' due to thrombocytopenia from platelet antibodies. This is more common in women who have been pregnant.
* Transfusion associated '''graft-versus-host disease''' (TA-GVHD)


==References==
==References==

Revision as of 22:16, 6 November 2008

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In medicine, erythrocyte transfusion or red blood cell transfusion is the "transfer of erythrocytes from a donor to a recipient or reinfusion to the donor."[1]

Adverse effects

For more information, see: Transfusion reaction.

Immunologic reactions

  • Febrile nonhemolytic transfusion reactions (FNHTR) due to destruction of incompatible donor white blood cells
  • Hemolytic reactions due to blood group incompatibility is "mismatch between donor and recipient blood. Antibodies present in the recipient's serum are directed against antigens in the donor product. Such a mismatch may result in a transfusion reaction in which, for example, donor blood is hemolyzed."[2]
    • Acute hemolytic transfusion reactions due to ABO incompatibility
    • Delayed hemolytic transfusion reactions
  • Allergic reactions
    • Anaphylactic transfusion reactions may occur, especially in patients with IgA-deficiency.
    • Urticaria may occur due to the recipient's IgE reacting to antigens from the donor.
  • Posttransfusion purpura (PTP) due to thrombocytopenia from platelet antibodies. This is more common in women who have been pregnant.
  • Transfusion associated graft-versus-host disease (TA-GVHD)

References

External links