CD4-positive T-lymphocyte: Difference between revisions
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In [[medicine]], the '''CD4-positive T-lymphocyte''' is "a critical subpopulation of [[T-lymphocyte]]s involved in the induction of most immunological functions. The [[Human Immunodeficiency Virus|HIV]] virus has selective tropism for the T4 cell which expresses the [[CD4 antigen|CD4]] phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes."<ref>{{MeSH}}</ref> | In [[medicine]], the '''CD4-positive T-lymphocyte''' is "a critical subpopulation of [[T-lymphocyte]]s involved in the induction of most immunological functions. The [[Human Immunodeficiency Virus|HIV]] virus has selective tropism for the T4 cell which expresses the [[CD4 antigen|CD4]] phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes."<ref>{{MeSH}}</ref> | ||
Revision as of 17:27, 22 August 2010
In medicine, the CD4-positive T-lymphocyte is "a critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes."[1]
The number of CD4-positive T-lymphocytes is called the CD4 lymphocyte count and it is reduced in Human Immunodeficiency Virus Type 1 and AIDS.
References
- ↑ Anonymous (2024), CD4-positive T-lymphocyte (English). Medical Subject Headings. U.S. National Library of Medicine.