Angiotensin II receptor antagonist
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Mechanism of action
Angiotensin II receptor antagonists block angiotensin II AT1 receptors.
Adverse effects
Angiotensin II receptor antagonists can cause hyperkalemia. The rise in potassium has been reported to be both similar to[1] and less that occurs with angiotensin-converting enzyme inhibitors.[2]
References
- ↑ The ONTARGET Investigators. 2008. Telmisartan, Ramipril, or Both in Patients at High Risk for Vascular Events. N Engl J Med 358, no. 15:1547-1559.
- ↑ Bakris GL, Siomos M, Richardson D, et al (2000). "ACE inhibition or angiotensin receptor blockade: impact on potassium in renal failure. VAL-K Study Group". Kidney Int. 58 (5): 2084–92. DOI:10.1111/j.1523-1755.2000.00381.x. PMID 11044229. Research Blogging.