CZ:Ref:DOI:10.1098/rstb.2005.1777: Difference between revisions

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  | last2 = Clare | first2 = S.
  | last2 = Clare | first2 = S.
  | year = 2006
  | year = 2006
  | title = Review. High-resolution MRI: in vivo histology?
  | title = High-resolution MRI: in vivo histology?
  | journal = Philosophical Transactions of the Royal Society B: Biological Sciences
  | journal = Philosophical Transactions of the Royal Society B: Biological Sciences
  | volume = 361
  | volume = 361
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  | url = http://journals.royalsociety.org/content/p080300686n880q6/
  | url = http://journals.royalsociety.org/content/p080300686n880q6/
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:Briefly reviews the state of the art of [[high resolution]] [[magnetic resonance imaging]] in the living [[brain]] and answers the question in the title basically positively. Quote from the conclusions: "While being able to understand the relationship between brain structure and function is likely to be crucial in attaining a complete understanding of the brain, the potential of this in vivo technique for understanding diseases of the brain is considerable. It is currently very difficult to detect many [[neurodegenerative disease]]s such as [[Alzheimer's disease|Alzheimer's]] and [[Parkinson's disease|Parkinson's]] until there has been considerable [[brain damage|damage]] to the brain and [[patient]]s have begun to show [[symptom]]s. If these [[disease]]s could be [[diagnostic imaging|detected]] at an earlier stage, the opportunities for pre-symptomatic [[treatment]] are much greater. In the future,  [[Magnetic resonance microscopy|high resolution magnetic resonance imaging]]  could become a standard method of detecting [[brain pathology|pathological changes in the brain]] at the earliest possible occasion, leading to treatment and the minimization of irreversible damage."

Latest revision as of 06:19, 20 January 2009

Bridge, H. & S. Clare (2006), "High-resolution MRI: in vivo histology?", Philosophical Transactions of the Royal Society B: Biological Sciences 361 (1465): 137–146, DOI:10.1098/rstb.2005.1777 [e]

Briefly reviews the state of the art of high resolution magnetic resonance imaging in the living brain and answers the question in the title basically positively. Quote from the conclusions: "While being able to understand the relationship between brain structure and function is likely to be crucial in attaining a complete understanding of the brain, the potential of this in vivo technique for understanding diseases of the brain is considerable. It is currently very difficult to detect many neurodegenerative diseases such as Alzheimer's and Parkinson's until there has been considerable damage to the brain and patients have begun to show symptoms. If these diseases could be detected at an earlier stage, the opportunities for pre-symptomatic treatment are much greater. In the future, high resolution magnetic resonance imaging could become a standard method of detecting pathological changes in the brain at the earliest possible occasion, leading to treatment and the minimization of irreversible damage."