Optic nerve glioma/Definition

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Optic nerve glioma [r]: Neuroglia-derived tumors arising from the optic nerve, usually presenting in childhood. Roughly 50% are associated with neurofibromatosis;. Clinical manifestations include decreased visual acuity; exopthalmos, pathologic nystagmus and strabismus; pallor or swelling of the optic disc; and intracranial hypertension; The tumor may extend into the optic chiasm and hypothalamus. (Adams et al., Principles of Neurology, 6th ed, p681)

This definition is at least in part based on: Anonymous (2023), Optic nerve glioma (English). Medical Subject Headings. U.S. National Library of Medicine.