File:Brain-disease-gyrification.png

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Title / Description


Gyrification in the human brain: Normal adult cortical surface (left), polymicrogyria (center) and lissencephaly (right).
Author(s)


Lefèvre and Mangin, 2010
Copyright holder


Lefèvre and Mangin, 2010
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Source


Part of Fig. 9 from Lefèvre J, Mangin JF (2010). "A reaction-diffusion model of human brain development". PLoS Comput Biol 6 (4): e1000749. DOI:10.1371/journal.pcbi.1000749. PMID 20421989. PMC PMC2858670. Research Blogging[e]
Based on modeling gyrification as a reaction-diffusion process, the authors provide a mechanism — compatible with the sulcal roots hypothesis — by which the folding process of the cerebral cortex can be explained, along with its anatomical variability and common malformations like polymicrogyria and lissencephaly.
Date created


November 11, 2009
Country of first publication


United States
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current20:21, 1 May 2010Thumbnail for version as of 20:21, 1 May 20101,794 × 550 (620 KB)Daniel Mietchen (Talk | contribs){{Image_Details |description = Gyrification in the human brain: Normal adult cortical surface (left), polymicrogyria (center) and lissencephaly (right). |author = Lefèvre and Mangin, 2010 |copyright = Lefèvre and Mangin, 2010 |source = Part of Fig. 9 from Lefèvre and Mangin, 2010 |date-created = November 11, 2009 |pub-country = United States |notes = |versions = }}
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