Carbamazepine

From Citizendium, the Citizens' Compendium
Jump to: navigation, search
This article is a stub and thus not approved.
Main Article
Talk
Related Articles  [?]
Bibliography  [?]
External Links  [?]
Citable Version  [?]
 
This editable Main Article is under development and not meant to be cited; by editing it you can help to improve it towards a future approved, citable version. These unapproved articles are subject to a disclaimer.
Carbamazepine.jpg
carbamazepine
IUPAC name: benzo[b][1]benzazepine-11-carboxamide
Synonyms: carbamezepine
Formula: C15H12N2O

 Uses: anticonvulsant

 Properties:

 Hazards:

Mass (g/mol): CAS #:
236.2686 298-46-4


Carbamazepine is an anticonvulsant drug used to treat epilepsy, grand mal seizures and psychomotor or focal seizures, neurologic pain, as from trigenimal neuralgia, psychiatric disorders including manic-depressive illness and dementia related aggression. Its three-dimensional structure and action is similar to that of phentoin despite being quite dissimilar chemically. It is also similar to the tricyclic antidepressant medications.[1]

Brand names

Adverse reactions

Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) may occur in patients with HLA-B*1502 allele who take carbamazepine.[2].

External links

The most up-to-date information about Carbamazepine and other drugs can be found at the following sites.


References

  1. Drug Bank page for Carbamazepine.
  2. Anonymous. Table of Valid Genomic Biomarkers in the Context of Approved Drug Labels. U.S. Food and Drug Administration