Metoclopramide

In medicine, metoclopramide is a " dopamine D2 antagonist that is used as an antiemetic."

In a randomized controlled trial that compared droperidol, metoclopramide, and prochlorperazine, droperidol was more effective but also caused more self-reported anxiety or restlessness.

Metoclopramide may cause akathisia, this is not prevented by diphenhydramine.