Drug interaction

In pharmacology, drug interactions are "the action of a drug that may affect the activity, metabolism, or toxicity of another drug."

Protein binding
These interactions are usually transient and mild until a new steady state is achieved. These are mainly for drugs without much first-pass liver metabolism. The principle plasma proteins for drug binding are: Some drug interactions with warfarin are due to changes in protein binding.
 * 1) albumin
 * 2) α1-acid glycoprotein
 * 3) lipoproteins

Cytochrome P450
Patients have abnormal metabolism by cytochrome P-450 due to either inheriting abnormal alleles or due to drug interactions. Tables are available to check for drug interactions due to cytochrome P-450 interactions. .