Acebutolol

Acebutolol is a cardioselective, beta-adrenergic antagonist (beta blocker) with relatively little effects, at low dosage, on bronchial receptors compared to other beta-blockers such as atenolol and propranolol. Epinephrine typically binds to these same receptors, subsequently raising heart rate and blood pressure, but this action is blocked when beta-blockers such as acebutolol bind to these receptors, thereby interferring with epinephrine binding. Blood pressure is also increased by the release of renin, a hormone produced in the kidneys, which narrows blood vessels. By preventing renin release, acebutolol reduces blood pressure by a second mechanism.Acebutolol at DrugBank