Selective serotonin uptake inhibitor

In medicine, serotonin uptake inhibitors are second-generation antidepressants that potentiate the effect of serotonin by blocking its uptake from the synaptic cleft.

Examples

 * Citalopram (generic). Can be combined with bupropion.
 * Duloxetine. Inhibits cytochrome P-450 CYP2D6.
 * Fluoxetine (generic). Inhibits cytochrome P-450 CYP2D6.
 * Paroxetine (generic). Inhibits cytochrome P-450 CYP2D6. May increase death from breast cancer among women taking tamoxifen.
 * Sertraline (generic)