BRCA2 gene

In physiology, BRCA2 gene (BRCA-2 gene) is "a tumor suppressor gene located on human chromosome 13 at locus 13q12.3. Mutations of this gene are associated with the formation of familial breast and ovarian cancer. It encodes a large, nuclear protein that is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements."