Carotid intima-media thickness

In medicine and cardiovascular disease, the carotid intima-media thickness (CIMT) is a surrogate outcome measure used in randomized controlled trials of the treatment of atherosclerosis. It is suggested that "an annual increase of 0.03 mm in intima–media thickness was associated with a tripling of the rate of coronary events."

A meta-analysis concludes "the modest relation between CIMT and coronary atherosclerosis most likely reflects variability in atherosclerosis development between the vascular beds rather than limitations of CIMT measurements."