Cytochrome P-450 CYP2D6

In biology, the cytochrome P-450 CYP2D6 is a "cytochrome P-450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as debrisoquine; adrenergic receptor antagonists; and tricyclic antidepressants. This enzyme is deficient in up to 10 percent of the Caucasian population."