Net efficacy adjusted for risk

In statistics, net efficacy adjusted for risk (NEAR) is a measure that combines measure of efficacy and risk into a single metric. For example, the relative risk of efficacy can be combined with the relative risk for drug toxicity into a single NEAR RR. Alternatively, the odds ratio of efficacy can be combined with the odds ratio for drug toxicity into a single NEAR OR.


 * $$\mbox{Net efficacy adjusted for risk (NEAR RR)} =\mbox{Relative risk for efficacy } \times \mbox{ Relative risk for harm}$$


 * $$\mbox{Net efficacy adjusted for risk (NEAR OR)} =\mbox{Odds ratio for efficacy } \times \mbox{ Odds ratio for harm}$$