Nephrotic syndrome

In medicine, nephrotic syndrome is "a condition characterized by severe proteinuria, greater than 3.5 g/day in an average adult. the substantial loss of protein in the urine results in complications such as hypoproteinemia; generalized edema; hypertension; and hyperlipidemias. diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction."

Spot protein/creatinine ratio
One study found that in the presence of stable renal function, a protein/creatinine ratio:
 * > 3.5 (mg/mg) suggests nephrotic syndrome
 * < 0.2 is within normal limits