Systemic inflammatory response syndrome

In medicine, systemic inflammatory response syndrome (SIRS) is "a systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions":
 * 1) fever >38°  C (100.4° F) or hypothermia <36° C (96.8° F)
 * 2) tachycardia >90 beat/minute
 * 3) tachypnea >24 breaths/minute;
 * 4) leukocytosis >12,000 cells/cubic mm or 10% immature forms

"While usually related to infection, SIRS can also be associated with noninfectious insults such as trauma; burns; or pancreatitis. If infection is involved, a patient with SIRS is said to have sepsis."

A minority of patients have positive blood cultures.