Bordetella pertussis

Description and Significance
Bordetella pertusis, commonly known as whooping cough, was first defined in the 16th century. It is a respiratory tract infection depicted by a paroxysmal cough. Bordetella pertusis is extremely tiny, and is a Gram-negative aerobic coccobacilius. It can appear in singles or in pairs. Before vaccinations were prevalent, Bordetella pertusis was a major cause of death among children and infants. After the pertusis vaccine was introduced, reported cases of this infection decreased by more than 99%. Even though this infection has been contained for the most part, it is still remains a disease that is of major concern.

Pathophysiology
Humans are the only home for Bordetella pertusis. Through aerosolized droplets from coughing, Bordetella pertusis is spread. This gram-negative pleomorphic bacillius attaches to and damages ciliated respiratory epithelium.